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USA:Polyester based Bioactive dressing surface
– a boom for injured personnel |
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2005-1-18
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Soldier faces two potent dangers besides enemy and they are life threatening injury and infection therefrom.
When no medical assistance is on call matters take a turn for worse.
Now there is hope with a new wound dressing surface developed by a University of Rhode Island textile chemist and the President of a Massachusetts biomedical firm, help is on hand for a battlefield soldier, as well as police officers, firefighters, hikers, rock climbers and emergency medical personnel.
It took partners for 14 years in research, Martin Bide, URI Professor of textiles, fashion merchandising and design, and Matthew Phaneuf, President of BioSurfaces, Ashland, Massachusetts, to invent a polyester based wound dressing surface that doubles up resisting infection on one hand while enhancing blood-clotting properties.
The process involves a polyester material with polyurethane being inlayed into the structure to provide the properties of elasticity. After the base material is modified chemically so that it provides anchor for protein attachment, a broad-spectrum antibiotic Cipro is incorporated into the polyester using textile dyeing technology, followed by the biologically-active agent thrombin, a pivotal enzyme in the clotting process.
“The specific protein, thrombin, kicks off the body''s clotting mechanism, and while that is working, the antibiotic is moving into the wound to prevent infection,” Phaneuf said.
Expressing confidence about their invention, Bide informed that they would continue to refine it, even as they were interested in taping companies, agencies or businesses interested in buying it.
The product allows an injured person or emergency medical worker to apply the bioactive surface simply by pulling this bioactive bandage out of a package and applying it to the wound site. The wound dressing surface frees the soldier''s hands to deal with other life-and-death issues. Without the new dressing, the injured soldier or medics must apply direct pressure with their hands, apply clotting and anti-infection medications, and then attach a bandage. The new product developed by Bide and Phaneuf eliminates nearly all of these steps.
The partnership began when Phaneuf, who is also the assistant director of the Vascular Surgery Research Laboratory at Beth Israel Deaconess Medical Center in Boston, mentioned to his wife, Tina, an obstacle he was facing in working with artificial arteries. Tina recommended that he speak with her former professor, Martin Bide, for some assistance.
Phaneuf and Bide clicked and the two used textile dyeing processes to enhance the impact of antibiotics in fighting infection in artificial arteries.
That collaboration led to their most recent work with wound dressing surfaces. “In little bits and pieces over the past several years dating back to our original work, we have been working on infection prevention techniques,” Phaneuf said.
“We have now developed something that provides pressure to a wound and is bioactive,” Phaneuf said.
Other bioactive agents could be added to a dressing to address other treatment issues, Bide said. “We have a multi-use textile with a multifaceted surface. We found a successful way to attach these chemical groups without degrading the polyester.”
Phaneuf said he and Bide have moved ahead due to their common interest in helping soldiers, firefighters, police officers and others facing life threatening situations to treat their wounds successfully. |
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